Characterization of signal bias at the GLP-1 receptor induced by backbone modification of GLP-1

Lignende værker

• β-Arrestin-biased agonists of the GLP-1 receptor from β-amino acid residue incorporation into GLP-1 analogues
  af: Hager, Marlies V., et al.
  Udgivet: (2016)
• Use of Backbone Modification to Enlarge the Spatiotemporal Diversity of Parathyroid Hormone Receptor-1 Signaling via Biased Agonism
  af: Liu, Shi, et al.
  Udgivet: (2019)
• Minireview: Signal Bias, Allosterism, and Polymorphic Variation at the GLP-1R: Implications for Drug Discovery
  af: Koole, Cassandra, et al.
  Udgivet: (2013)
• Impact of substitution registry on receptor-activation profiles of backbone-modified glucagon-like peptide-1 analogues
  af: Cary, Brian P., et al.
  Udgivet: (2019)
• Second Extracellular Loop of Human Glucagon-like Peptide-1 Receptor (GLP-1R) Has a Critical Role in GLP-1 Peptide Binding and Receptor Activation
  af: Koole, Cassandra, et al.
  Udgivet: (2012)