Bone marrow-derived cPLA2α contributes to renal fibrosis progression

The group IVA calcium-dependent cytosolic phospholipase A2 (cPLA2α) enzyme directs a complex “eicosanoid storm” that accompanies the tissue response to injury. cPLA2α and its downstream eicosanoid mediators are also implicated in the pathogenesis of fibrosis in many organs, including the kidney. We...

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Vydáno v:J Lipid Res
Hlavní autoři: Montford, John R., Lehman, Allison M. B., Bauer, Colin D., Klawitter, Jelena, Klawitter, Jost, Poczobutt, Joanna M., Scobey, Micah, Weiser-Evans, Mary, Nemenoff, Raphael A., Furgeson, Seth B.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Biochemistry and Molecular Biology 2018
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5794431/
https://ncbi.nlm.nih.gov/pubmed/29229740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M082362
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