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Inhibition of 5-lipoxygenase decreases renal fibrosis and progression of chronic kidney disease
In inflammatory diseases, the 5-lipoxygenase (5-LO) pathway contributes to epithelial damage and fibrosis by catalyzing the production of leukotrienes (LTs). Antagonists of the 5-LO pathway are currently approved for use in patients and are well tolerated. We found that expression of 5-LO is strongl...
Gardado en:
| Publicado en: | Am J Physiol Renal Physiol |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Physiological Society
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6483031/ https://ncbi.nlm.nih.gov/pubmed/30649890 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00262.2018 |
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