Bone marrow-derived cPLA2α contributes to renal fibrosis progression

The group IVA calcium-dependent cytosolic phospholipase A2 (cPLA2α) enzyme directs a complex “eicosanoid storm” that accompanies the tissue response to injury. cPLA2α and its downstream eicosanoid mediators are also implicated in the pathogenesis of fibrosis in many organs, including the kidney. We...

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Detalhes bibliográficos
Publicado no:J Lipid Res
Main Authors: Montford, John R., Lehman, Allison M. B., Bauer, Colin D., Klawitter, Jelena, Klawitter, Jost, Poczobutt, Joanna M., Scobey, Micah, Weiser-Evans, Mary, Nemenoff, Raphael A., Furgeson, Seth B.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5794431/
https://ncbi.nlm.nih.gov/pubmed/29229740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M082362
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