Bone marrow-derived cPLA2α contributes to renal fibrosis progression

The group IVA calcium-dependent cytosolic phospholipase A2 (cPLA2α) enzyme directs a complex “eicosanoid storm” that accompanies the tissue response to injury. cPLA2α and its downstream eicosanoid mediators are also implicated in the pathogenesis of fibrosis in many organs, including the kidney. We...

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Veröffentlicht in:J Lipid Res
Hauptverfasser: Montford, John R., Lehman, Allison M. B., Bauer, Colin D., Klawitter, Jelena, Klawitter, Jost, Poczobutt, Joanna M., Scobey, Micah, Weiser-Evans, Mary, Nemenoff, Raphael A., Furgeson, Seth B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Biochemistry and Molecular Biology 2018
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Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5794431/
https://ncbi.nlm.nih.gov/pubmed/29229740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M082362
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