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Modeling hypercholesterolemia and vascular lipid accumulation in LDL receptor mutant zebrafish
Elevated plasma LDL cholesterol is the dominant risk factor for the development of atherosclerosis and cardiovascular disease. Deficiency in the LDL receptor (LDLR) is a major cause of familial hypercholesterolemia in humans, and the LDLR knockout mouse is a major animal model of atherosclerosis. He...
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| Publicado no: | J Lipid Res |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Biochemistry and Molecular Biology
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5794413/ https://ncbi.nlm.nih.gov/pubmed/29187523 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.D081521 |
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