Identifying specificity groups in the T cell receptor repertoire

T cell receptor (TCR) sequences are very diverse, with many more possible sequence combinations than T cells in any one individual(1–4). Here we define the minimal requirements for TCR antigen specificity, through an analysis of TCR sequences using a panel of peptide and major histocompatibility com...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nature
Egile Nagusiak: Glanville, Jacob, Huang, Huang, Nau, Allison, Hatton, Olivia, Wagar, Lisa E., Rubelt, Florian, Ji, Xuhuai, Han, Arnold, Krams, Sheri M., Pettus, Christina, Haas, Nikhil, Lindestam Arlehamn, Cecilia S., Sette, Alessandro, Boyd, Scott D., Scriba, Thomas J., Martinez, Olivia M., Davis, Mark M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2017
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5794212/
https://ncbi.nlm.nih.gov/pubmed/28636589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature22976
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