Src Kinase and Syk Activation Initiate PI3K Signaling by a Chimeric Latent Membrane Protein 1 in Epstein-Barr Virus (EBV)+ B Cell Lymphomas

The B lymphotrophic γ-herpesvirus EBV is associated with a variety of lymphoid- and epithelial-derived malignancies, including B cell lymphomas in immunocompromised and immunosuppressed individuals. The primary oncogene of EBV, latent membrane protein 1 (LMP1), activates the PI3K/Akt pathway to indu...

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Hlavní autoři: Hatton, Olivia, Lambert, Stacie L., Krams, Sheri M., Martinez, Olivia M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3411813/
https://ncbi.nlm.nih.gov/pubmed/22880054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0042610
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