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ACTIVATION OF THE JAK/STAT PATHWAY IN EPSTEIN BARR VIRUS(+) ASSOCIATED POST TRANSPLANT LYMPHOPROLIFERATIVE DISEASE: ROLE OF INTERFERON-γ
Epstein Barr virus (EBV) is associated with B cell lymphomas in post-transplant lymphoproliferative disease (PTLD). Latent membrane protein 1 (LMP1), the major oncogenic protein of EBV, promotes tumorigenesis through activation of NF-κB, Erk, p38, JNK, and Akt. The Jak/STAT signal transduction pathw...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2774223/ https://ncbi.nlm.nih.gov/pubmed/19656130 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-6143.2009.02781.x |
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