ACTIVATION OF THE JAK/STAT PATHWAY IN EPSTEIN BARR VIRUS(+) ASSOCIATED POST TRANSPLANT LYMPHOPROLIFERATIVE DISEASE: ROLE OF INTERFERON-γ

Epstein Barr virus (EBV) is associated with B cell lymphomas in post-transplant lymphoproliferative disease (PTLD). Latent membrane protein 1 (LMP1), the major oncogenic protein of EBV, promotes tumorigenesis through activation of NF-κB, Erk, p38, JNK, and Akt. The Jak/STAT signal transduction pathw...

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Bibliografiske detaljer
Main Authors: Vaysberg, Maria, Lambert, Stacie L., Krams, Sheri M., Martinez, Olivia M.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2774223/
https://ncbi.nlm.nih.gov/pubmed/19656130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-6143.2009.02781.x
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