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Tumor-derived Variants of Epstein-Barr Virus Latent Membrane Protein 1 Induce Sustained Erk Activation and c-Fos

Latent membrane protein 1 (LMP1) of Epstein-Barr virus (EBV) is a proven oncogene that is essential for transformation of human B cells by the virus. LMP1 induces constitutive activation of several signal transduction pathways involving nuclear factor κB, phosphatidylinositol 3-kinase/Akt, and the m...

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Detalhes bibliográficos
Main Authors: Vaysberg, Maria, Hatton, Olivia, Lambert, Stacie L., Snow, Andrew L., Wong, Bonnie, Krams, Sheri M., Martinez, Olivia M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2605991/
https://ncbi.nlm.nih.gov/pubmed/18986987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M802968200
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