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The Repertoire Dissimilarity Index as a method to compare lymphocyte receptor repertoires

BACKGROUND: The B and T cells of the human adaptive immune system leverage a highly diverse repertoire of antigen-specific receptors to protect the human body from pathogens. The sequencing and analysis of immune repertoires is emerging as an important tool to understand immune responses, whether be...

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Pubblicato in:BMC Bioinformatics
Autori principali: Bolen, Christopher R., Rubelt, Florian, Vander Heiden, Jason A., Davis, Mark M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5340033/
https://ncbi.nlm.nih.gov/pubmed/28264647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-017-1556-5
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