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Individual heritable differences result in unique cell lymphocyte receptor repertoires of naïve and antigen-experienced cells

The adaptive immune system's capability to protect the body requires a highly diverse lymphocyte antigen receptor repertoire. However, the influence of individual genetic and epigenetic differences on these repertoires is not typically measured. By leveraging the unique characteristics of B, CD...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Rubelt, Florian, Bolen, Christopher R., McGuire, Helen M., Heiden, Jason A. Vander, Gadala-Maria, Daniel, Levin, Mikhail, M. Euskirchen, Ghia, Mamedov, Murad R., Swan, Gary E., Dekker, Cornelia L., Cowell, Lindsay G., Kleinstein, Steven H., Davis, Mark M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5191574/
https://ncbi.nlm.nih.gov/pubmed/27005435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11112
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