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High capacity of the endoplasmic reticulum to prevent secretion and aggregation of amyloidogenic proteins
Protein aggregation is associated with neurodegeneration and various other pathologies. How specific cellular environments modulate the aggregation of disease proteins is not well understood. Here, we investigated how the endoplasmic reticulum (ER) quality control system handles β‐sheet proteins tha...
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| Publicado no: | EMBO J |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5793802/ https://ncbi.nlm.nih.gov/pubmed/29247078 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201695841 |
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