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Evolutionary expansion of DNA hypomethylation in the mammalian germline genome

DNA methylation in the germline is among the most important factors influencing the evolution of mammalian genomes. Yet little is known about its evolutionary rate or the fraction of the methylome that has undergone change. We compared whole-genome, single-CpG DNA methylation profiles in sperm of se...

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Dettagli Bibliografici
Pubblicato in:Genome Res
Autori principali: Qu, Jianghan, Hodges, Emily, Molaro, Antoine, Gagneux, Pascal, Dean, Matthew D., Hannon, Gregory J., Smith, Andrew D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5793779/
https://ncbi.nlm.nih.gov/pubmed/29259021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.225896.117
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