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Hide and seek: how chromatin-based pathways silence retroelements in the mammalian germline
Mobile elements comprise a major fraction of most mammalian genomes. To protect their fitness and stability, hosts must keep mobile elements in check in their germline. In most tissues mobile element insertions are decorated with chromatin modifications suggestive of transcriptional silencing. Howev...
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| Pubblicato in: | Curr Opin Genet Dev |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4914476/ https://ncbi.nlm.nih.gov/pubmed/26821364 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gde.2015.12.001 |
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