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Hide and seek: how chromatin-based pathways silence retroelements in the mammalian germline

Mobile elements comprise a major fraction of most mammalian genomes. To protect their fitness and stability, hosts must keep mobile elements in check in their germline. In most tissues mobile element insertions are decorated with chromatin modifications suggestive of transcriptional silencing. Howev...

詳細記述

保存先:
書誌詳細
出版年:Curr Opin Genet Dev
主要な著者: Molaro, Antoine, Malik, Harmit S.
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4914476/
https://ncbi.nlm.nih.gov/pubmed/26821364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gde.2015.12.001
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