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Multiple LINEs of retrotransposon silencing mechanisms in the mammalian germline

Retrotransposons play an important role in genome evolution but pose acute challenges to host genome integrity, particularly in early stage germ cells where epigenetic control is relaxed to permit genome-wide reprogramming. In most species, the inability to silence retrotransposons in the germline i...

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Bibliografische gegevens
Gepubliceerd in:Semin Cell Dev Biol
Hoofdauteurs: Yang, Fang, Wang, P. Jeremy
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5011444/
https://ncbi.nlm.nih.gov/pubmed/26957474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcdb.2016.03.001
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