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Multiple LINEs of retrotransposon silencing mechanisms in the mammalian germline
Retrotransposons play an important role in genome evolution but pose acute challenges to host genome integrity, particularly in early stage germ cells where epigenetic control is relaxed to permit genome-wide reprogramming. In most species, the inability to silence retrotransposons in the germline i...
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Publicado no: | Semin Cell Dev Biol |
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Main Authors: | , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5011444/ https://ncbi.nlm.nih.gov/pubmed/26957474 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcdb.2016.03.001 |
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