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Unconventional translation of mammalian LINE-1 retrotransposons

Long Interspersed Element-1 (LINE-1 or L1) retrotransposons encode proteins required for their mobility (ORF1p and ORF2p), yet little is known about how L1 mRNA is translated. Here, we show that ORF2 translation generally initiates from the first in-frame methionine codon of ORF2, and that both ORF1...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Alisch, Reid S., Garcia-Perez, Jose L., Muotri, Alysson R., Gage, Fred H., Moran, John V.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Cold Spring Harbor Laboratory Press 2006
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1356112/
https://ncbi.nlm.nih.gov/pubmed/16418485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1380406
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