Epigenetic Control of Mammalian LINE-1 Retrotransposon by Retinoblastoma Proteins

Long interspersed nuclear elements (LINEs or L1 elements) are targeted for epigenetic silencing during early embryonic development and remain inactive in most cells and tissues. Here we show that E2F-Rb family complexes participate in L1 elements epigenetic regulation via nucleosomal histone modific...

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Autors principals: Montoya-Durango, Diego E., Liu, Yongqing, Teneng, Ivo, Kalbfleisch, Ted, Lacy, Mary E., Steffen, Marlene C., Ramos, Kenneth S.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3418809/
https://ncbi.nlm.nih.gov/pubmed/19427507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrfmmm.2009.02.011
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