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Reactivation of L1 retrotransposon by benzo(a)pyrene involves complex genetic and epigenetic regulation

Benzo(a)pyrene (BaP), is an environmental pollutant present in tobacco smoke and a byproduct of fossil fuel combustion that likely contributes to the tumorigenic processes in human cancers including lung and esophageal. Long Interspersed Nuclear Element-1 (LINE-1) or L1 is a mobile element within th...

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Detalhes bibliográficos
Main Authors: Teneng, Ivo, Montoya-Durango, Diego E, Quertermous, James L, Lacy, Mary E, Ramos, Kenneth S
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3092684/
https://ncbi.nlm.nih.gov/pubmed/21150308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.6.3.14282
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