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Assessment of genetic variation for the LINE-1 retrotransposon from next generation sequence data

BACKGROUND: In humans, copies of the Long Interspersed Nuclear Element 1 (LINE-1) retrotransposon comprise 21% of the reference genome, and have been shown to modulate expression and produce novel splice isoforms of transcripts from genes that span or neighbor the LINE-1 insertion site. RESULTS: In...

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Detalhes bibliográficos
Main Authors: Rouchka, Eric, Montoya-Durango, Diego E, Stribinskis, Vilius, Ramos, Kenneth, Kalbfleisch, Ted
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2967742/
https://ncbi.nlm.nih.gov/pubmed/21044359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-11-S9-S12
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