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Multiple LINEs of retrotransposon silencing mechanisms in the mammalian germline

Retrotransposons play an important role in genome evolution but pose acute challenges to host genome integrity, particularly in early stage germ cells where epigenetic control is relaxed to permit genome-wide reprogramming. In most species, the inability to silence retrotransposons in the germline i...

詳細記述

保存先:
書誌詳細
出版年:Semin Cell Dev Biol
主要な著者: Yang, Fang, Wang, P. Jeremy
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5011444/
https://ncbi.nlm.nih.gov/pubmed/26957474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcdb.2016.03.001
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