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Development of a Deimmunized Bispecific Immunotoxin dDT2219 against B-Cell Malignancies

Diphtheria toxin (DT) related targeted toxins are effective in cancer treatment, but efficacy diminishes in time because of their immunogenic potential and/or former vaccinations. In order to overcome this limitation for DT2219, a promising bispecific targeted toxin which targets CD19 and CD22, we d...

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書目詳細資料
發表在:Toxins (Basel)
Main Authors: Schmohl, Joerg U., Todhunter, Deborah, Taras, Elizabeth, Bachanova, Veronika, Vallera, Daniel A.
格式: Artigo
語言:Inglês
出版: MDPI 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5793119/
https://ncbi.nlm.nih.gov/pubmed/29316610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins10010032
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