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Development of a Deimmunized Bispecific Immunotoxin dDT2219 against B-Cell Malignancies
Diphtheria toxin (DT) related targeted toxins are effective in cancer treatment, but efficacy diminishes in time because of their immunogenic potential and/or former vaccinations. In order to overcome this limitation for DT2219, a promising bispecific targeted toxin which targets CD19 and CD22, we d...
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| Vydáno v: | Toxins (Basel) |
|---|---|
| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
MDPI
2018
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5793119/ https://ncbi.nlm.nih.gov/pubmed/29316610 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins10010032 |
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