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Sphingomyelin and GM1 Influence Huntingtin Binding to, Disruption of, and Aggregation on Lipid Membranes
[Image: see text] Huntington disease (HD) is an inherited neurodegenerative disease caused by the expansion beyond a critical threshold of a polyglutamine (polyQ) tract near the N-terminus of the huntingtin (htt) protein. Expanded polyQ promotes the formation of a variety of oligomeric and fibrillar...
Tallennettuna:
| Julkaisussa: | ACS Omega |
|---|---|
| Päätekijät: | , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
American Chemical Society
2018
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| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5793032/ https://ncbi.nlm.nih.gov/pubmed/29399649 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.7b01472 |
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