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Blockade of ACK1/TNK2 To Squelch the Survival of Prostate Cancer Stem-like Cells
Prostate cancer stem-like cells (PCSCs) are not only enriched in the CD44(+)PSA(−/lo) subpopulation but also employ androgen-independent signaling mechanisms for survival. CD44(+) PCSCs defy androgen deprivation, resist chemo- and radiotherapy and are highly tumorigenic. Human prostate tissue microa...
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| Опубликовано в: : | Sci Rep |
|---|---|
| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group UK
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5792546/ https://ncbi.nlm.nih.gov/pubmed/29386546 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-20172-z |
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