Aβ mediates F-actin disassembly in dendritic spines leading to cognitive deficits in Alzheimer's disease

Dendritic spine loss is recognized as an early feature of Alzheimer's disease (AD), but the underlying mechanisms are poorly understood. Dendritic spine structure is defined by filamentous actin (F-actin) and we observed depolymerization of synaptosomal F-actin accompanied by increased globular...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Kommaddi, Reddy Peera, Das, Debajyoti, Karunakaran, Smitha, Nanguneri, Siddharth, Bapat, Deepti, Ray, Ajit, Shaw, Eisha, Bennett, David A., Nair, Deepak, Ravindranath, Vijayalakshmi
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2018
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5792472/
https://ncbi.nlm.nih.gov/pubmed/29246925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2127-17.2017
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados