Repetitive intradermal bleomycin injections evoke T-helper cell 2 cytokine-driven pulmonary fibrosis

IL-4 and IL-13 are major T-helper cell (Th) 2 cytokines implicated in the pathogenesis of several lung diseases, including pulmonary fibrosis. In this study, using a novel repetitive intradermal bleomycin model in which mice develop extensive lung fibrosis and a progressive decline in lung function...

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Veröffentlicht in:Am J Physiol Lung Cell Mol Physiol
Hauptverfasser: Singh, Brijendra, Kasam, Rajesh K., Sontake, Vishwaraj, Wynn, Thomas A., Madala, Satish K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2017
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5792179/
https://ncbi.nlm.nih.gov/pubmed/28775096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00184.2017
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