Hsp90 regulation of fibroblast activation in pulmonary fibrosis

Idiopathic pulmonary fibrosis (IPF) is a severe fibrotic lung disease associated with fibroblast activation that includes excessive proliferation, tissue invasiveness, myofibroblast transformation, and extracellular matrix (ECM) production. To identify inhibitors that can attenuate fibroblast activa...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Sontake, Vishwaraj, Wang, Yunguan, Kasam, Rajesh K., Sinner, Debora, Reddy, Geereddy B., Naren, Anjaparavanda P., McCormack, Francis X., White, Eric S., Jegga, Anil G., Madala, Satish K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5313067/
https://ncbi.nlm.nih.gov/pubmed/28239659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.91454
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