Preferential use of unmutated immunoglobulin heavy variable region genes in Boxer dogs with chronic lymphocytic leukemia

Human chronic lymphocytic leukemia (CLL) is a clinically heterogeneous disease, and immunoglobulin heavy variable region (IGHV) gene mutational status is an important prognostic marker. IGHV mutational status has not been previously examined in canine CLL. We sequenced the IGHV-D-J rearrangements fr...

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Detaylı Bibliyografya
Yayımlandı:PLoS One
Asıl Yazarlar: Rout, Emily D., Burnett, Robert C., Labadie, Julia D., Yoshimoto, Janna A., Avery, Anne C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2018
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5791963/
https://ncbi.nlm.nih.gov/pubmed/29385200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0191205
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