Total Proteome Analysis Identifies Migration Defects as a Major Pathogenetic Factor in Immunoglobulin Heavy Chain Variable Region (IGHV)-unmutated Chronic Lymphocytic Leukemia

The mutational status of the immunoglobulin heavy chain variable region defines two clinically distinct forms of chronic lymphocytic leukemia (CLL) known as mutated (M-CLL) and unmutated (UM-CLL). To elucidate the molecular mechanisms underlying the adverse clinical outcome associated with UM-CLL, t...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Mol Cell Proteomics
Autori principali: Eagle, Gina L., Zhuang, Jianguo, Jenkins, Rosalind E., Till, Kathleen J., Jithesh, Puthen V., Lin, Ke, Johnson, Gillian G., Oates, Melanie, Park, Kevin, Kitteringham, Neil R., Pettitt, Andrew R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Biochemistry and Molecular Biology 2015
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4390271/
https://ncbi.nlm.nih.gov/pubmed/25645933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M114.044479
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi