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Total Proteome Analysis Identifies Migration Defects as a Major Pathogenetic Factor in Immunoglobulin Heavy Chain Variable Region (IGHV)-unmutated Chronic Lymphocytic Leukemia
The mutational status of the immunoglobulin heavy chain variable region defines two clinically distinct forms of chronic lymphocytic leukemia (CLL) known as mutated (M-CLL) and unmutated (UM-CLL). To elucidate the molecular mechanisms underlying the adverse clinical outcome associated with UM-CLL, t...
Shranjeno v:
izdano v: | Mol Cell Proteomics |
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Main Authors: | , , , , , , , , , , |
Format: | Artigo |
Jezik: | Inglês |
Izdano: |
The American Society for Biochemistry and Molecular Biology
2015
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Teme: | |
Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4390271/ https://ncbi.nlm.nih.gov/pubmed/25645933 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M114.044479 |
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