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Pan-cancer analysis of somatic copy number alterations implicates IRS4 and IGF2 in enhancer hijacking
Extensive prior research has focused on somatic copy-number alterations (SCNAs) affecting cancer genes, yet the extent to which recurrent SCNAs exert their influence through rearranging cis-regulatory elements remains unclear. Here, we present a framework for inferring cancer-related gene overexpres...
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| Publicado en: | Nat Genet |
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| Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5791882/ https://ncbi.nlm.nih.gov/pubmed/27869826 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.3722 |
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