AMKL chimeric transcription factors are potent inducers of leukemia

Acute megakaryoblastic leukemia in patients without Down syndrome is a rare malignancy with a poor prognosis. RNA sequencing of fourteen pediatric cases previously identified novel fusion transcripts that are predicted to be pathologic including CBFA2T3-GLIS2, GATA2-HOXA9, MN1-FLI, and NIPBL-HOXB9....

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Udgivet i:Leukemia
Main Authors: Dang, Jinjun, Nance, Stephanie, Ma, Jing, Cheng, Jinjun, Walsh, Michael P., Vogel, Peter, Easton, John, Song, Guangchun, Rusch, Michael, Gedman, Amanda Larson, Koss, Cary, Downing, James R., Gruber, Tanja A.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5791746/
https://ncbi.nlm.nih.gov/pubmed/28174417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2017.51
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