Preclinical analysis of sodium valproate for the treatment of pediatric diffuse intrinsic pontine glioma and adult glioblastoma

Epigenetic dysregulation is evident in high grade glioma, particularly diffuse intrinsic pontine glioma (DIPG), which often present with histone mutations and 46% of adult glioblastomas (GBM) harbour at least one mutation of an epigenetic regulator. Cell viability assays were used to investigate the...

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Pubblicato in:Neuro Oncol
Autori principali: Killick-Cole, Clare, Bienemann, Ali, Singleton, Will, Wyatt, Marcella, Asby, Daniel, Boulter, Lisa, Haynes, Harry, Barua, Neil, Gill, Steven
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2018
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Abstracts
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5791607/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox238.065
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