miRNA-23a/CXCR4 regulates neuropathic pain via directly targeting TXNIP/NLRP3 inflammasome axis

BACKGROUND: Chemokine CXC receptor 4 (CXCR4) in spinal glial cells has been implicated in neuropathic pain. However, the regulatory cascades of CXCR4 in neuropathic pain remain elusive. Here, we investigated the functional regulatory role of miRNAs in the pain process and its interplay with CXCR4 an...

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Dades bibliogràfiques
Publicat a:J Neuroinflammation
Autors principals: Pan, Zhiqiang, Shan, Qun, Gu, Pan, Wang, Xiao Min, Tai, Lydia Wai, Sun, Menglan, Luo, Xin, Sun, Liting, Cheung, Chi Wai
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2018
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5791181/
https://ncbi.nlm.nih.gov/pubmed/29386025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-018-1073-0
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