miRNA-23a/CXCR4 regulates neuropathic pain via directly targeting TXNIP/NLRP3 inflammasome axis

BACKGROUND: Chemokine CXC receptor 4 (CXCR4) in spinal glial cells has been implicated in neuropathic pain. However, the regulatory cascades of CXCR4 in neuropathic pain remain elusive. Here, we investigated the functional regulatory role of miRNAs in the pain process and its interplay with CXCR4 an...

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Bibliografski detalji
Izdano u:J Neuroinflammation
Glavni autori: Pan, Zhiqiang, Shan, Qun, Gu, Pan, Wang, Xiao Min, Tai, Lydia Wai, Sun, Menglan, Luo, Xin, Sun, Liting, Cheung, Chi Wai
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2018
Teme:
Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5791181/
https://ncbi.nlm.nih.gov/pubmed/29386025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-018-1073-0
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