Central Administration of C-X-C Chemokine Receptor Type 4 Antagonist Alleviates the Development and Maintenance of Peripheral Neuropathic Pain in Mice

AIM: To explore the roles of C-X-C chemokine receptor type 4 (CXCR4) in spinal processing of neuropathic pain at the central nervous system (CNS). METHODS: Peripheral neuropathic pain (PNP) induced by partial sciatic nerve ligation (pSNL) model was assessed in mice. Effects of a single intrathecal (...

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Detalhes bibliográficos
Main Authors: Luo, Xin, Tai, Wai Lydia, Sun, Liting, Qiu, Qiu, Xia, Zhengyuan, Chung, Sookja Kim, Cheung, Chi Wai
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4132096/
https://ncbi.nlm.nih.gov/pubmed/25119456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0104860
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