Enhanced and Selective Antiproliferative Activity of Methotrexate-Functionalized-Nanocapsules to Human Breast Cancer Cells (MCF-7)

Methotrexate is a folic acid antagonist and its incorporation into nanoformulations is a promising strategy to increase the drug antiproliferative effect on human breast cancer cells by overexpressing folate receptors. To evaluate the efficiency and selectivity of nanoformulations containing methotr...

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Veröffentlicht in:Nanomaterials (Basel)
Hauptverfasser: de Oliveira, Catiúscia P., Büttenbender, Sabrina L., Prado, Willian A., Beckenkamp, Aline, Asbahr, Ana C., Buffon, Andréia, Guterres, Silvia S., Pohlmann, Adriana R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5791111/
https://ncbi.nlm.nih.gov/pubmed/29300349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nano8010024
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