Methotrexate-loaded lipid-core nanocapsules are highly effective in the control of inflammation in synovial cells and a chronic arthritis model

BACKGROUND: Rheumatoid arthritis (RA) is the most common autoimmune disease in the word, affecting 1% of the population. Long-term prognosis in RA was greatly improved following the introduction of highly effective medications such as methotrexate (MTX). Despite the importance of this drug in RA, 8%...

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Vydáno v:Int J Nanomedicine
Hlavní autoři: Boechat, Antônio Luiz, de Oliveira, Catiúscia Padilha, Tarragô, Andrea Monteiro, da Costa, Allyson Guimarães, Malheiro, Adriana, Guterres, Silvia Stanisçuaski, Pohlmann, Adriana Raffin
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2015
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4622525/
https://ncbi.nlm.nih.gov/pubmed/26543364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S85369
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