Methotrexate diethyl ester-loaded lipid-core nanocapsules in aqueous solution increased antineoplastic effects in resistant breast cancer cell line

Breast cancer is the most frequent cancer affecting women. Methotrexate (MTX) is an antimetabolic drug that remains important in the treatment of breast cancer. Its efficacy is compromised by resistance in cancer cells that occurs through a variety of mechanisms. This study evaluated apoptotic cell...

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Détails bibliographiques
Auteurs principaux: Yurgel, Virginia C, Oliveira, Catiuscia P, Begnini, Karine R, Schultze, Eduarda, Thurow, Helena S, Leon, Priscila MM, Dellagostin, Odir A, Campos, Vinicius F, Beck, Ruy CR, Guterres, Silvia S, Collares, Tiago, Pohlmann, Adriana R, Seixas, Fabiana K
Format: Artigo
Langue:Inglês
Publié: Dove Medical Press 2014
Sujets:
Original Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3970944/
https://ncbi.nlm.nih.gov/pubmed/24741306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S56506
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