Enhanced and Selective Antiproliferative Activity of Methotrexate-Functionalized-Nanocapsules to Human Breast Cancer Cells (MCF-7)

Methotrexate is a folic acid antagonist and its incorporation into nanoformulations is a promising strategy to increase the drug antiproliferative effect on human breast cancer cells by overexpressing folate receptors. To evaluate the efficiency and selectivity of nanoformulations containing methotr...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nanomaterials (Basel)
Prif Awduron: de Oliveira, Catiúscia P., Büttenbender, Sabrina L., Prado, Willian A., Beckenkamp, Aline, Asbahr, Ana C., Buffon, Andréia, Guterres, Silvia S., Pohlmann, Adriana R.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2018
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5791111/
https://ncbi.nlm.nih.gov/pubmed/29300349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nano8010024
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