The antiproliferative effect of indomethacin-loaded lipid-core nanocapsules in glioma cells is mediated by cell cycle regulation, differentiation, and the inhibition of survival pathways

Despite recent advances in radiotherapy, chemotherapy, and surgical techniques, glioblastoma multiforme (GBM) prognosis remains dismal. There is an urgent need for new therapeutic strategies. Nanoparticles of biodegradable polymers for anticancer drug delivery have attracted intense interest in rece...

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Detalles Bibliográficos
Autores principales: Bernardi, Andressa, Frozza, Rudimar L, Hoppe, Juliana B, Salbego, Christianne, Pohlmann, Adriana R, Battastini, Ana Maria O, Guterres, Sílvia S
Formato: Artigo
Lenguaje:Inglês
Publicado: Dove Medical Press 2013
Materias:
Original Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3578504/
https://ncbi.nlm.nih.gov/pubmed/23440594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S40284
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