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The antiproliferative effect of indomethacin-loaded lipid-core nanocapsules in glioma cells is mediated by cell cycle regulation, differentiation, and the inhibition of survival pathways

Despite recent advances in radiotherapy, chemotherapy, and surgical techniques, glioblastoma multiforme (GBM) prognosis remains dismal. There is an urgent need for new therapeutic strategies. Nanoparticles of biodegradable polymers for anticancer drug delivery have attracted intense interest in rece...

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書誌詳細
主要な著者: Bernardi, Andressa, Frozza, Rudimar L, Hoppe, Juliana B, Salbego, Christianne, Pohlmann, Adriana R, Battastini, Ana Maria O, Guterres, Sílvia S
フォーマット: Artigo
言語:Inglês
出版事項: Dove Medical Press 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3578504/
https://ncbi.nlm.nih.gov/pubmed/23440594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S40284
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