The antiproliferative effect of indomethacin-loaded lipid-core nanocapsules in glioma cells is mediated by cell cycle regulation, differentiation, and the inhibition of survival pathways

Despite recent advances in radiotherapy, chemotherapy, and surgical techniques, glioblastoma multiforme (GBM) prognosis remains dismal. There is an urgent need for new therapeutic strategies. Nanoparticles of biodegradable polymers for anticancer drug delivery have attracted intense interest in rece...

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Detalhes bibliográficos
Main Authors: Bernardi, Andressa, Frozza, Rudimar L, Hoppe, Juliana B, Salbego, Christianne, Pohlmann, Adriana R, Battastini, Ana Maria O, Guterres, Sílvia S
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2013
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3578504/
https://ncbi.nlm.nih.gov/pubmed/23440594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S40284
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