Development of a UPLC–MS/MS method for determination of pimavanserin tartrate in rat plasma: Application to a pharmacokinetic study

A simple, rapid and sensitive method based on an ultra-performance liquid chromatography–tandem mass spectrometry (UPLC–MS/MS) has been developed and validated for the determination of pimavanserin in rat plasma. The analyte was extracted by protein precipitation with methanol and separated on an AC...

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Detalhes bibliográficos
Publicado no:J Pharm Anal
Main Authors: Wang, Shixiao, Wang, Yang, Gao, Shuang, Zhang, Yuanyuan, Wang, Hanpei, Zhao, Longshan, Bi, Kaishun, Wang, Shaojie, Chen, Xiaohui
Formato: Artigo
Idioma:Inglês
Publicado em: Xi'an Jiaotong University 2017
Assuntos:
Original Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5790751/
https://ncbi.nlm.nih.gov/pubmed/29404067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpha.2017.07.004
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