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A safe and highly efficient tumor-targeted type I interferon immunotherapy depends on the tumor microenvironment
Despite approval for the treatment of various malignancies, clinical application of cytokines such as type I interferon (IFN) is severely impeded by their systemic toxicity. AcTakines (Activity-on-Target cytokines) are optimized immunocytokines that, when injected in mice, only reveal their activity...
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| Wydane w: | Oncoimmunology |
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| Główni autorzy: | , , , , , , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Taylor & Francis
2017
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5790344/ https://ncbi.nlm.nih.gov/pubmed/29399401 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1398876 |
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