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Reactive oxygen species and small-conductance calcium-dependent potassium channels are key mediators of inflammation-induced hypotension and shock

Septic shock is associated with life-threatening vasodilation and hypotension. To cause vasodilation, vascular endothelium may release nitric oxide (NO), prostacyclin (PGI2), and the elusive endothelium-derived hyperpolarizing factor (EDHF). Although NO is critical in controlling vascular tone, inhi...

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Main Authors: Cauwels, Anje, Rogge, Elke, Janssen, Ben, Brouckaert, Peter
Format: Artigo
Jezik:Inglês
Izdano: Springer-Verlag 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2921058/
https://ncbi.nlm.nih.gov/pubmed/20496172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-010-0633-2
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