Maturation of hematopoietic stem cells from prehematopoietic stem cells is accompanied by up-regulation of PD-L1

Hematopoietic stem cells (HSCs) mature from pre-HSCs that originate in the major arteries of the embryo. To identify HSCs from in vitro sources, it will be necessary to refine markers of HSCs matured ex vivo. We purified and compared the transcriptomes of pre-HSCs, HSCs matured ex vivo, and fetal li...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Tober, Joanna, Maijenburg, Marijke M.W., Li, Yan, Gao, Long, Hadland, Brandon K., Gao, Peng, Minoura, Kodai, Bernstein, Irwin D., Tan, Kai, Speck, Nancy A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2018
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5789403/
https://ncbi.nlm.nih.gov/pubmed/29282253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20161594
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