Developmental trajectory of prehematopoietic stem cell formation from endothelium

Hematopoietic stem and progenitor cells (HSPCs) in the bone marrow are derived from a small population of hemogenic endothelial (HE) cells located in the major arteries of the mammalian embryo. HE cells undergo an endothelial to hematopoietic cell transition, giving rise to HSPCs that accumulate in...

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Bibliographische Detailangaben
Veröffentlicht in:Blood
Hauptverfasser: Zhu, Qin, Gao, Peng, Tober, Joanna, Bennett, Laura, Chen, Changya, Uzun, Yasin, Li, Yan, Howell, Elizabeth D., Mumau, Melanie, Yu, Wenbao, He, Bing, Speck, Nancy A., Tan, Kai
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2020
Schlagworte:
Hematopoiesis and Stem Cells
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7426642/
https://ncbi.nlm.nih.gov/pubmed/32392346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2020004801
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