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Translocation Breakpoints Preferentially Occur in Euchromatin and Acrocentric Chromosomes
Chromosomal translocations drive the development of many hematological and some solid cancers. Several factors have been identified to explain the non-random occurrence of translocation breakpoints in the genome. These include chromatin density, gene density and CCCTC-binding factor (CTCF)/cohesin b...
Gespeichert in:
| Veröffentlicht in: | Cancers (Basel) |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
MDPI
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5789363/ https://ncbi.nlm.nih.gov/pubmed/29316705 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers10010013 |
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