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Chromosome arm aneuploidies shape tumour evolution and drug response

Chromosome arm aneuploidies (CAAs) are pervasive in cancers. However, how they affect cancer development, prognosis and treatment remains largely unknown. Here, we analyse CAA profiles of 23,427 tumours, identifying aspects of tumour evolution including probable orders in which CAAs occur and CAAs p...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Shukla, Ankit, Nguyen, Thu H. M., Moka, Sarat B., Ellis, Jonathan J., Grady, John P., Oey, Harald, Cristino, Alexandre S., Khanna, Kum Kum, Kroese, Dirk P., Krause, Lutz, Dray, Eloise, Fink, J. Lynn, Duijf, Pascal H. G.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6978319/
https://ncbi.nlm.nih.gov/pubmed/31974379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-14286-0
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