Overexpression of the E2F target gene CENPI promotes chromosome instability and predicts poor prognosis in estrogen receptor-positive breast cancer

During cell division, chromosome segregation is facilitated by the mitotic checkpoint, or spindle assembly checkpoint (SAC), which ensures correct kinetochore-microtubule attachments and prevents premature sister-chromatid separation. It is well established that misexpression of SAC components on th...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Thangavelu, Pulari U., Lin, Cheng-Yu, Vaidyanathan, Srividya, Nguyen, Thu H.M., Dray, Eloise, Duijf, Pascal H.G.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5617495/
https://ncbi.nlm.nih.gov/pubmed/28977935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19131
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